Identification and Characterization of Antioxidants from Sophora flavescens
نویسندگان
چکیده
منابع مشابه
Tyrosinase inhibitory prenylated flavonoids from Sophora flavescens.
For the purpose of the development of a skin-whitening agent, Sophora flavescens was evaluated for tyrosinase inhibitory activity and its active principles were identified following activity-guided isolation. The ethanol extract and dichloromethane fraction from S. flavescens showed significant inhibition of mushroom tyrosinase. From the dichloromethane fraction, three known prenylated flavonoi...
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Pterocarpans (1-3) and flavanones (4-10) were isolated from Sophora flavescens and screened for their ability to inhibit neuraminidase (an enzyme crucial in the proliferation of the influenza virus). The majority of inhibitors were shown to have IC(50) values of 20 microM or below. Interestingly, pterocarpan 1 emerged as the best inhibitor with an IC(50) of 1.4 microM. We were thus able to prov...
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In this paper, microwave-assisted extraction (MAE) of oxymatrine from Sophora flavescens were studied by HPLC-photodiode array detection. Effects of several experimental parameters, such as concentration of extraction solvent, ratio of liquid to material, microwave power, extraction temperature, and extraction time on the extraction efficiencies of oxymatrine were evaluated. The optimal extract...
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Acyl-coenzyme A:cholesterol acyltransferase (ACAT, EC 2.3.1.26) is the primary cellular enzyme that catalyzes the formation of cholesteryl esters from cholesterol and fatty acyl-coenzyme A. It has been identified that two isoenzymes, ACAT-1 and ACAT-2, have different cell locations, membrane orientations, and metabolic functions. Atherosclerotic lesions are associated with the accumulation of c...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2006
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.29.1911